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5. Substance-related disorders

The substance-related disorders include abuse of a drug, adverse effects of any medication, and exposure to toxic substances. The DSM-IV lists II types of substances: alcohol, amphetamines, caffeine, cannabis, cocaine, hallucinogens, inhalants, nicotine, opioids. phencycltdine (PCP), and the group sedatives, hypnotics, and anxiolytics. Polysubstance dependence and other or unknown substance-related disorders to toxins or prescribed or over-the-counter medications are also included.

Substance Abuse Disorders
DSM-IV CATEGORIES
Alcohol Use Disorders
303.90 Alcohol dependence
305.00 Alcohol abuse
Amphetamine Use Disorders
304.40 Amphetamine dependence
305.70 Amphetamine abuse
Cannabis Use Disorders
304.30 Cannabis dependence
305.20 Cannabis abuse
Cocaine Use Disorders
304.20 Cocaine dependence
305.60 Cocaine abuse
Hallucinogen Use Disorders
304.50 Hallucinogen dependence
305 30 Hallucinogen abuse
Inhalant Use Disorders
304.60 Inhalant dependence
305.90 Inhalant abuse
Nicotine Use Disorder
305.10 Nicotine dependence
Opioid Use Disorders
304.00 Opioid dependence
305.50 Opioid abuse
Phencyclidine Use Disorders
304.90 Phencyclidine dependence
305.90 Phencyclidine abuse
Sedative, Hypnotic, or Anxiolytic Use Disorders
304.10 Sedative, hypnotic, or anxiolytic dependence
305.40 Sedative, hypnotic, or anxiolytic abuse
Polysubstance-Related Disorder
304.80 Polysubstance dependence
Other (or Unknown) Substance Use Disorders
304.90 Other (or unknown) substance dependence
305.90 Other (or unknown) substance abuse

SUBSTANCE DEPENDENCE

With substance dependence, the client experiences cognitive, behavioral, and physiologic symptoms generated from persistent use. The client continues to take the drug despite the health problems that occur. The habit of constant drug use usually follows the pattern of tolerance, withdrawal, and compulsive drug-taking behavior.

Tolerance is defined as either the need for increased amounts of the substance to establish the desired effect, or a decreased effect with continued use of the substance in the same amount. Individuals develop different degrees of tolerance. The amount of drug necessary to cause tolerance in a person who habitually uses the drug could be lethal to a person who doesn't use the drug.

Withdrawal occurs when the tissue and blood levels of the substance decrease in a person who has engaged in prolonged. heavy use of the substance. When the uncomfortable withdrawal symptoms occur, the person usually takes the drug to relieve or decrease the symptoms. A common pattern is to initiate drug use shortly after awakening.

The person experiences withdrawal symptoms specific to the drug used. Major physical signs of withdrawal are seen with alcohol, opioids, sedatives, hypnotics, and anxiolytics. Less obvious physical signs are noted with amphetamines, cocaine, nicotine, and cannabis, but subjective symptoms can be intense if the client is withdrawing from heavy use. Insignificant withdrawal symptoms are seen even with chronic use of hallucinogens and PCP

With compulsive drug use, the substance is taken in significant amounts for a longer period than was originally intended. There is recognition that the use is excessive, and the client has desired or unsuccessfully attempted to decrease or control the use. Even though physical and psychological problems have occurred from use of the substance, the person continues to use the drug despite evidence of the problems it is causing. A great deal of energy continues to be expended in obtaining the substance, taking the substance, and recovering from its effects. The client also sustains intoxication and withdrawal symptoms, often at inappropriate times, such as when expected to fulfill obligations at home, work, or school. Major social, occupational, and recreational activities are sacrificed for the substance use despite the recurrence of negative effects. With continued use, a tolerance to the substance develops, necessitating increased amounts to achieve previous levels of intoxication. This pattern of substance tolerance, withdrawal, and compulsive use has been noted in every category of substances with the exception of caffeine.

Some people may exhibit a pattern of compulsive drug use without manifesting signs of tolerance or withdrawal. In contrast, others can develop a tolerance and experience withdrawal symptoms without having used the drug compulsively.

SUBSTANCE ABUSE

The major characteristic of substance abuse is the maladaptive behavior pattern that occurs with repeated use of the drug. The person is unable to manage typical role responsibilities at work, home, or school. There is a recurrent pattern of being in situations that are physically hazardous, such as driving while intoxicated, or engaging in high-risk leisure activities, such as rock climbing. Often there are substance-related legal issues, such as driving under the influence of a drug, or disorderly conduct. The person continues to take the substance despite a history of interpersonal, familial, and social problems that are instigated or exaggerated because of the use of the substance.

A substance abuse diagnosis is used when the dysfunctional behaviors recur over a 12-month period. Abuse continues despite knowledge of the problems and dangers it causes. Unlike substance dependence, the diagnosis of substance abuse doesn't include tolerance, withdrawal, or a pattern of compulsive use: rather, it focuses on the detrimental effects of the person's repeated use of the drug.

To help clients understand behaviors associated with substance abuse disorder, it is important to share with them current knowledge of the biological and psychological roots of addiction. Although no specific genes for alcoholism have been identified, alcoholism does run in families. Children of alcoholics have a fourfold greater chance of becoming addicted than children of non-alcoholics. Research has further shown that individuals who are prone to alcoholism have low levels of monoamine oxidase and acetaldehyde dehydrogenase. A certain part of the brain, the medial forebrain bundle, is believed to be associated with positive reinforcement of drug and alcohol use. Many other variables, especially environmental factors and personality traits, play a maior role in determining whether or not a person will become drug-dependent.

In working with clients who have substance-related disorders, it is essential for the nurse to know the routes of administration as well as the main effects of the drugs. (For further information, see Characteristic Effects From Use of Major Substances, pages 87 to 90, and Common Withdrawal Symptoms Associated With Psychoactive Drugs, pages 91 to 93.)

CAHARACTERISTIC EFFECTS FROM USE OF MAJOR SUBSTANCES
DRUG CLASSIFICATION ROUTE OF ADMINISTRATION EFFECTS (In order of increasing sympton severity)
Alcohol Oral
  • Relaxation and sedation
  • Decreased inhibition
  • Lack of coordination and unsteady gait
  • Slurred speech
  • Nausea and vomiting
  • Transient visual, tactile, or auditory hallucinations
  • Severe anxiety
  • Psychomotor agitation
  • High potential for permanent damage to liver or brain
Amphetamines (dexedrine, methamphetamine, ice uppers, crank, speed). Oral or injected
  • Grandiosity
  • Hypervigilance
  • Hypertension or hypotension
  • Tachycardia or bradycardia speed)
  • Mydriasis (dilated pupils)
  • Euphoria
  • Appetite suppression
  • Personality changes
  • Antisocial behavior
  • Schizophrenic episodes
Cannabis (marijuana, grass, pot, hashish, joint, weed.TCH) Smoked or injected
  • Mild intoxication
  • Increased appetite
  • Dry mouth
  • Lack of coordination
  • Impaired judgment and memory
  • Sexual arousal
  • Tachycardia
  • Visual hallucinations
Cocaine (coke, snow, lady, powder, crack) Oral, injected, or inhaled
  • Talkativeness
  • Grandiosity
  • Hypervigilance
  • Anxiety
  • Impaired judgment
  • Tachycardia or bradycardia
  • Hypertension or hypotension
  • Mydriasis (dilated pupils)
  • Muscle twitching
  • Respiratory depression
  • Hallucinations, paranoid delusions or paranoia
  • Formication (sensation of insectos crawling on the skin)
  • Personality Changes
  • Antisocial behavior
  • Euphoria followed by depression and feeling let down
Hallucinogens (lysergic acid diethylamide a.k.a. LSD or acid, peyote, Psilocybin, mescaline Oral or inhaled
  • Intensified perceptions and feelings
  • Synesthesia ( seeing sound or hearing colour)
  • Visual, auditory, or tactile hallucinations
  • Fear of losing one's mind
  • Mydrtasis(dilated pupils)
  • Tachycardia anci palpitations
  • Blurred vision
  • Dizziness, weakness, and tremors
  • Altered perceptions (flashbacks)
  • Impaired judgment and bizarre behavior
  • Mood swings and psychotic like symptoms
Inhalants (sprayInhaled can propellants, paint products and solvents, glue, gasoline, cleaning fluid) Inhaled
  • Euphoria and giddiness
  • Headache
  • Dizziness, fatigue, or drowsiness
  • Nystagmus (involuntary, rapid movement of the eye)
  • Unsteady gait or tremors
  • Slurred speech
  • Blurred vision or diplopia (double vision)
  • Damage to lungs, liver, and kidneys
Opioids (morphine, codeine, methadone, dilaudid, heroin a.k.a. smack or horse Oral, injected, or inhaled
  • Immediate euphoria followed by dysphoria
  • Psychomotor retardation or agitation
  • Slurred speech
  • Impaired judgment and memory
  • Sedation and respiratory depression
  • Constricted pupils
  • Decreased sexual and aggressive drives
Phencyclidine (PCP, angel dust, hog) Oral, injected, or inhaled
  • Grandiosity and illusions of strength
  • Impulsiveness
  • Psychomotor agitation
  • Assaultive behavior
  • Decreased sensory awareness
  • Hypertension and tachycardia
  • Unsteady gait and lack of coordination
  • Nystagmus (involuntary, rapid movement of the eye)
  • Mood swings and paranoia
Sedatives, hypnotics, or anxiolytics (such as secobarbital sodium [Seconal], pentobarbital sodium [Nembutal], diazepam [Valium], alprazolam [Xanax], chlordiazepoxide [Libriurn]) Oral or injected
  • Unsteady gait and lack of coordination
  • Slurred speech
  • Nystagmus (involuntary, rapid movement of the eye)
  • Sedation
  • Impaired judgment
  • Inappropriate sexual behavior and aggressive drives
  • Mood swings
Nicotine Oral or inhaled
  • Tachycardia
  • Vasoconstriction
  • Irritation of the oral mucosa
  • Persistent cough (smoker's cough)
  • Damaged alveoli and bronchioli
  • Emphysema
  • High potential for oral, laryn-geal, or lung cancer
  • Stimulation of senses
  • Alertness and enhanced performance
  • Anxiety and restlessness
Caffeine oral
  • flushed face
  • Talkativeness
  • Tremors or muscle twitching
  • Tachycardia or arrhythmias
  • Insomnia
  • Irritation of the stomach

COMMON WITHDRAWAL SYMPTONS ASSOCIATED WITH PSYCHOACTIVE DRUGS
DRUG CLASSIFICATION MAJOR WITHDRAWAL SYMPTON
Alcohol
  • Nausea and vomiting
  • Tremors and weakness
  • Sweating*
  • Tachycardia and hypertension*
  • Delusions*
  • Agitated behavior*
  • Hallucinations and nocturnal illusions*

* indicates the symptoms of alcohol withdrawal syndrome

Amphetamines
  • Dysphoria
  • Disorientation
  • Fatigue and depression with suicidal potential
  • Disturbed sleep and unpleasant dreams
  • Hallucinations or delusions
Caffeine
  • Irritability and nervousness
  • Inability to concentrate
  • Headache
  • Tremors
  • Lethargy
  • Impaired psychomotor performance
Cannabis
  • No acute withdrawal symptoms; symptoms appear over varying time periods after withdrawal
  • Amotivational syndrome (inability to concentrate or complete tasks)
  • Chronic respiratory problems
  • Memory and learning difficulty
  • Suppressed prolactin and testosterone levels
Cocaine
  • Severe craving for drug
  • Severe depression ("postcoke blues")
  • Fatigue
  • Psychomotor agitation or retardation
  • Anxiety
  • Insomnia or hypersomnia
  • Increased appetite
Hallucinogens
  • Symptoms appear over varying time periods after withdrawal
  • Apprehension, fear, or panic
  • Hyperactivity
  • Sweating
  • Tachycardia
  • Altered perceptions (flashbacks)
  • Perceptual distortions, especially hallucinations
Inhalants
  • Symptoms appear over varying time periods after withdrawal
  • Central nervous system damage (cerebral atrophy or peripheral neuropathies)
  • Anxiety and tremors
  • Sleep disturbances
  • Acute or chronic renal failure
  • Bone marrow depression
  • Cardiac arrhythmias
  • Respiratory damage (lung or sinus damage, pneumonitis, emphysema, lung changes, or respiratory depression)
  • Liver disease (hepatitis or cirrhosis)
Nicotine
  • Irritability and nervousness
  • Headache
  • Inability to concentrate
  • Craving for tobacco
  • Increased appetite
  • Fatigue and dizziness
  • Tremors and palpitations
Opioids
  • Dysphoria
  • Anxiety
  • Insomnia
  • Increased respirations and yawning
  • Sweating
  • Lacrimation and rhinorrhea (nasal discharge)
  • Tremors and muscle twitching
  • Mydriasis (dilated pupils)
  • Piloerectlon ("goosebumps")
  • Nausea, abdominal cramps, and vomiting
Phencyclidine
  • Symptoms may appear over varying time periods after withdrawal
  • Anxiety
  • Withdrawn, catatonic state
  • Hypertension
  • Seizures
  • Bizarre behavior and speech associated with temporary psychosis
Sedatives, hypnotics, anxiolytlcs
  • Anxiety and agitation or
  • Sweating
  • Tachycardia
  • Tremors
  • Nausea and vomiting
  • Insomnia and disturbing dreams
  • Transient visual, auditory, or tactile hallucinations
  • Seizures

COMMUNICATION STRATEGIES

NURSING DIAGNOSIS: INEEFCTIVE DENIAL
Probable CausesDefining Characteristics
  • Severe, anxiety-provoking situations
  • Threat to role or self-esteem
  • Feelings of guilt and shame
  • Sense of inadequacy as a person
  • Feelings of vulnerability
  • Misperceptions of reality
  • No comprehension of problem
  • Lack of supportive relatiorships
  • Unnecessary risk taking
  • Refusal to discuss troublesome situations

Long-Term Goal
The client will verbalize accountability for personal actions and recognize the relationship between substance abuse and personal problems.

Short-Term Goal #1:The client will verbalize that a substance abuse problem exists.

Interventions and Rationales

Short-Term Goal #2: The client will verbalize a decreased need for denial as a coping mechanism to solve personal problems.

Interventions and Rationales

NURSING DIAGNOSIS: INEFFECTIVE INDIVIDUAL COPING
Probable CausesDefining Characteristics
  • Dysfunctional family
  • Lack of parental role modeling
  • Family history of substance abuse
  • Chronic anxiety
  • Impaired or nonexistent support system
  • Inability to problem solve
  • Verbalization of feelings of inadequacy
  • Limited or no peer contacts to serve as role models
  • Inability to meet basic needs
  • Inability to delay gratification

Long-Term Goal
The client will develop various problem-solving skills and access to a support system to assist in coping with both long-term and short-term stressors.

Short-Term Goal #1:The client will identify and discuss the major stressors that influence daily functioning.

Interventions and Rationales

Short-Term Goal #2: The client will explore alternative behaviors that can be used to cope with identified stressors.

Interventions and Rationales

NURSING DIAGNOSIS: SENSORY/PERCEPTUAL ALTERATIONS, INCLUDING VISUAL AND AUDITORY HALLUCINATIONS
Probable CausesDefining Characteristics
  • Severe anxiety
  • Substance withdrawal or use
  • Central nervous system damage
  • Metabolic response to trauma or severe stress
  • Delirium
  • Preoccupation/lack of awareness of environment
  • Lack of attention to personal hygiene and self-care
  • Verbalization of strong fear
  • Bizarre or impulsive behaviors
  • Rapid mood swings

Long-Term Goal
The client will complete the detoxification period and sustain no physical or emotional injury.

Short-Term Goal #1:The client will work with the nurse to remain safe during the detoxification period.

Interventions and Rationales

  • Determine the client's level of intoxication, and monitor the withdrawal symptoms related to the specific substance. The collection of baseline data is essential before instituting appropriate nursing interventions.
  • Closely supervise a client who is experiencing hallucinations or delusions. Thought disorganization, misinterpretation of stimuli, and the escalation of anxiety increase the danger of the clients acting impulsively or losing control. Safety becomes the first nursing priority.
  • Orient the client on a frequent basis or as needed. The nurse must present reality to the client to lessen confusion.
  • Short-Term Goal #2: The client will respond appropriately to stimuli and develop an accurate perception of the environment.

    Interventions and Rationales

  • Do not reinforce a hallucination by arguing, doubting, or questioning whether or not it is real; rather, point out that the nurse does not hear or see what the client does. The nurse gently helps the client to see that the hallucinations are not real.
  • Tell the client that hallucinations occur more frequently during the acute phases of substance intoxication or withdrawal and during recovery periods, when the client is experiencing increased physiologic and psychological distress. Many clients do not have knowledge about the effects that substances have on the body and need to understand that hallucinations occur during intoxication, withdrawal, and recovery periods.
  • Teach the client strategies, such as stress-management techniques and verbalization of thoughts and feelings, to decrease stress and deal with the situations that precipitate sensory alteration. Strategies that decrease stress or other triggers of hallucinations can refocus the clients attention on other stimuli or on more productive strategies to meet personal needs.
  • NURSING DIAGNOSIS: RISK FOR INJURY
    Probable CausesDefining Characteristics
    • Physiologic problems associated with withdrawal period from a chemical substance
    • Cognitive impairment and impaired judgment due to central nervous system damage
    • Disorientation and confusion
    • Poor impulse control
    • Inability to problem solve
    • Seizures
    • Tremors, poor muscle coordination, and impaired balance

    Long-Term Goal
    The client will not injure self or others during the course of treatment.

    Short-Term Goal #1:The client will recognize the stressors, such as physical health problems, fatigue, and interpersonal conflicts, that increase the risk of injury.

    Interventions and Rationales

  • Teach the client to assess, monitor, and obtain assistance for sensory-perceptual alterations that may occur. Sensory perceptual alterations can trigger acting out behaviors that may increase the client's risk of injury.
  • Discuss the symptoms of withdrawal and how to handle fearful and uncomfortable feelings. Identification of early symptons alerts the client that intervention is needed to prevent injury.
  • Teach the client to identify personal and environmental risk for injury. It is essential for the client to evaluate his own safety needs and level of vulnerability.
  • Instruct the client to track stressors and the current level of anxiety daily by keeping a log about stressful circumstances and how they are handled. The client needs to notice and evaluate how current anxiety and stress are handled.
  • Explore with the client how stress was handled in the past, and analyze the effectiveness of those coping methods. Exploration of the past can help the client identify previous healthy coping stratigies.
  • Identify health conditions that put the client at risk for injury by monitoring vital signs, tremors, and problems with coordination. Give medications that can decrease the occurrence or seizure activity. Prompt and ongoing nursing intervention can decrease the potential for seizure injuries and injuries related sensory problems.
  • Short-Term Goal #2: The client will demonstrate impulse control and appropriate judgment in stressful situations.

    Interventions and Rationales

  • Help the client evaluate his ability to make judgment, problem solve, and look at his capacity to control strong emotions. This information provides a baseline for determining which impulse control skills the client needs to learn and the most appropriate intervntion to use.
  • Identify any cognitive impairment that interferes with the client's ability to make judgments and control impulses. If the client has cognitive impairment, the nursing care must be adapter to address this additional need.
  • Role play stressful situations with the client. The client needs to learn and practice ways to master stressful situations and experience self-control.
  • NURSING DIAGNOSIS: KNOWLEDGE DEFICIT ABOUT THE EFFECTS OF SUBSTANCE ABUSE
    Probable CausesDefining Characteristics
    • History of learning difficulties
    • Denial of the risks and problems associated with substance use
    • Family history of substance abuse
    • Cognitive impairment
    • Beliefs in myths about substance use
    • Current or recent use of substances
    • Verbalization of misconceptions and misinformation
    • Verbalization of lack of knowledge
    • Verbalization of confusion
    • Denial of substance dependence use or abuse

    Long-Term Goal
    The client will verbalize understanding of the reasons for abstaining from the drug.

    Short-Term Goal #1:The client will verbalize the effects of substance use on the body and mind and state the reasons a specific drug is harmful.

    Interventions and Rationales

  • Evaluate the client's misperceptions about substance abuse. A baseline is needed, along with an overview of the client's misperceptions, myths, and knowledge deficits, to construct a comprehensive teaching plan.
  • Assess the client's ability to learn, readiness to learn, and level of anxiety. It is important to know whether the client's current situation facilitates or impedes the learning process.
  • Establish a teaching plan that includes concepts about substance abuse, physiologic and psychological effects of drugs, nutritional information, treatment modalities, assertiveness training, communication skills, coping strategies, family dynamics, self-help and after-care groups, dangers and risk behaviors associated with drug use, and relapse prevention. Client education is essential for promoting recovery.
  • Include the family or significant others in some or all parts of the teaching. Significant others can play a major role in facilitating the client's recovery by supporting the client through stressful times.
  • Short-Term Goal #2: The client will acknowledge that recovery from substance abuse requires changing prior habits and lifestyle.

    Interventions and Rationales

  • Help the client examine how lifestyle changes can affect the family. It is important to remember that a change in one family member influences the entire family system.
  • Help the client explore the differences between substance abuse and substance dependence. The client must realize the dangers involved with both types of behaviors to prevent future problems from occurring.
  • Help the client to understand the importance of aftercare to the success of the recovery period. Participation in aftercare groups significantly improves the client's chance of maintaining recovery from substance abuse or dependence.
  • Help the client explore how to avoid the people, places, and situations of the former lifestyle that may trigger relapse. Changing the clients lifestyle is the focal point for maintaining abstinence during the recovery period.
  • TWELVE STEPS OF ALCOHOLICS ANONYMOUS
    1. We admit we were powerless over alcohol, that our lives had become unmanageable.
    2. Came to believe that a Power greater than ourselves could restore us to sanity.
    3. Made a decision to turn our wills and lives over to the care of God as we understand Him.
    4. Made a searching and fearless moral inventory of ourselves.
    5. Admitted to God, to ourselves, and to another human being the exact nature of our wrongs.
    6. Were entirely ready to have God remove all these defects of character.
    7. Humbly asked Him to remove our shortcomings.
    8. Made a list of all persons we had harmed, and became willing to make amends to them all.
    9. Made direct amends to such people whenever possible, except when to do so would injure them or others.
    10. Continued to take personal inventory and when we were wrong promptly admitted it.
    11. Sought through prayer and meditation to improve our conscious contact i with God as we understood Him, praying only for knowledge of His will for us and the power to carry it out.
    12. Having had a spiritual awakening as a result of these steps, we tried to carry this message to alcoholics and to practice these principles in all our affairs.

    From Alcoholics Anonymous World Services, Inc. Twelve steps and twelve traditions. New York: The A.A. Grapevine and Alcoholics Anonymous Publishing, 1952.

    THERAPIES
    Detoxification (inpatient or outpatient day treatment programs)
    Rehabilitation (inpatient or outpatient day treatment programs)
    Aftercare (community or outpatient mental health centers)
    Residential Therapeutic Communities (self-regulating communities that operate on the premise that substance use is a symptom of emotional immaturity or a character disorder)
    Alcoholics Anonymous/Narcotics Anonymous
    Individual Substance Abuse Counseling/Therapy
    Group Therapy
    Family Therapy
    MEDICATIONS
    FAMILY CARE
    A Therapeutic Intervention