Panic Disorder

Self-Study Examination

Instructions: After studying the text answer the following true/false or multiple choice questions.  Remember, there's only one answer to each question.

1. Select the incorrect statement from the following:

a) The diagnosis of panic disorder requires the presence of at least four of the thirteen symptoms that develop abruptly and reach a crescendo within 10 minutes, typically lasting 10 minutes or so.
b) Besides a detailed clinical assessment of the presenting complaints and history, the diagnosis of panic disorder requires positive laboratory tests.
c) Panic attacks may also occur during sleep.
d) To satisfy the diagnostic criteria for panic disorder, at least some of the panic attacks must occur spontaneously.

2. Men are just as likely as women to be diagnosed with panic disorder.

a) True
b) False

3. Many patients discontinue pharmacological treatment before therapeutic benefits occur due to the drugs' side effects. The attrition rate is the highest with:

a) tricyclic antidepressants
b) MAO inhibitors
c) benzodiazepines

4. _____ have a rapid onset of action with immediate reduction of panic symptoms, lending themselves to be used on "as needed" basis.

a) tricyclics
b) MAO inhibitors
c) benzodiazepines

5. Select the incorrect statement from the following:

a) More than half of patients with mental illness in the United States are treated exclusively within the general medical care system rather than in the mental health system.
b) One-third to one-half of psychiatric illnesses are not accurately diagnosed by their physicians.
c) Many patients suffering from a mental illness present with somatic complaints to avoid the stigma of mental illness.
d) Antianxiety medications are among the most frequently prescribed medications in the United States.
e) none of the above

6. Which of the following statements does not accurately describe the behavior of a patient with panic disorder when he goes to the movies?

a) He would go only if accompanied by his spouse or a friend.
b) He would forgo the movie if he could not find anyone to go with.
c) He would go because he does not want to miss a good movie.
d) He would occupy an isle seat in the last row or near an exit.

7. Throughout history, many terms have been advanced to describe panic disorder. One of the following, however, is not one such term:

a) soldier's heart
b) neurasthenia
c) cardiac neurosis
d) hypocondria
e) effort phobia

8. Select the incorrect statement from the following:

a) Recent studies have estimated that as many as 2-3% of the population may have panic disorder.
b) Three times as many women are affected by panic disorder as men.
c) The onset of panic disorder is generally after the age of thirty.
d) Panic disorder tends to be a relapsing, remitting illness.

9. Select the incorrect statement from the following:

a) Most patients with panic disorder are able to link their disorder to stressful life events.
b) Panic disorder is a familial disease.
c) Panic disorder generally begins in the context of stressful life events.
d) Patients with panic disorder often grew up as children with uncommon fears and were more anxious than other children.

10. Patients with panic disorder are likely to present with many corn plaints. Select from the following the least likely symptom complaint

a) cardiac symptoms
b) gastrointestinal symptoms
c) neurologic symptoms
d) anxiety and depression symptoms

11. Select from the following the incorrect statement:

a) Most patients who meet the criteria for somatization disorder are also likely to meet the criteria for panic disorder.
b) Patients who satisfy both the criteria for somatization and panic disorder should be diagnosed with panic disorder and treated pharmacologically.
c) According to DSM-ffl, diagnosis of somatization disorder requires identification of thirteen symptoms from a list of 35.
d) Several studies have shown that patients with chest pain are four times as likely to have panic disorder as those without chest pains.
e) Patients with chest pain and panic disorder have a high likelihood of suffering myocardial infarction.

12. Which of the following statements is not true?

a) An overwhelming majority of patients with somatization disorder also meet criteria for panic disorder.
b) Symptoms such as chest pain, palpitations, shortness ofbreath, and dizziness are common symptoms for both disorders.
c) Somatization disorder is a chronic, severe condition with no known specific treatment whereas panic disorder is highly treatable.
d) all of the above
e) none of the above

13. A vast majority of patients with panic disorder develop a major depression at some time in their lives.

a) True
b) False

14. An episode of major depression almost always follows an episode of panic disorder; it rarely precedes it.

a) True
b) False

15. Diagnostic criteria for psychoactive substance abuse includes all of the following except:

a) frequent episodes of major depression
b) frequent intoxication or withdrawal symptoms
c) recurrent use of the substance despite adverse consequences to health, vocation, family and social life
d) a great deal of time spent in acquiring the substance, using it, or recovering from its effects
e) increased tolerance for the substance

16. Diagnostic criteria for generalized anxiety disorder includes all of the following except:

a) unrealistic or excessive worry about one or more life circumstances for six months or longer during which the patient is bothered more days than not by these concerns.
b) presence of at least six of eighteen symptoms from three categories
c) anxiety or worry about having a panic attack
d) all of the above

17. Many patients diagnosed with social phobia are able to handle social situations. Although fearful of them, they do so without avoiding them or they endure them with intense anxiety.

a) True
b) False

18. Tricyclic antidepressants have been found effective in patients with simple phobia.

a) True
b) False

19. Researchers have reported strong links between panic disorder and posttraumatic stress disorder (PTSD).

a) True
b) False

20. The area of the brain that is the central control mechanism for autonomic nervous system is known as

a) cerebral cortex
b) locus ceruleus
c) amygdala
d) thyroid gland

21. Many studies have found that patients with panic disorder have a significantly higher rate of hypertension and peptic ulcer disease.

a) True
b) False

22. Many studies have reported an increased prevalance of panic disorder in mitral valve prolapse (MVP) patients.

a) True
b) False

23. In medical patients with severe anxiety, the best initial course of action the physician must take is to

a) treat panic disorder separately or concurrently with the medical condition.
b) focus on any chronic medical illness that could precipitate anxiety.
c) review all drugs that the patient is taking that could cause anxiety.
d) b and c above.
e) all of the above

24. Medical disorders and substances that can mimic panic disorder symptoms include all of the following except.

a) hyperthyroidism
b) hypoglycemia
c) acute familial and financial crises
d) cocaine
e) coronary artery disease

25. Many studies have shown that patients with panic disorder have an abnormal increase in thyroid function.

a) True
b) False

26. Many research studies have established hypoglycemia as a cause of panic disorder.

a) True
b) False

27. According to most clinical studies, few patients with pheochromocytoma meet criteria for panic disorder.

a) True
b) False

28. There are many similarities between temporal lobe epilepsy and panic disorder. However, TLE can be differentiated by all of the following except:

a) altered state of consciousness
b) progression into other types of epilepsy
c) flushing, hyperventilation and tachycardia
d) hallucinations
e) psychic behavior with episodes of deja vu or jamais vu

29. Marijuana, cocaine, amphetamines or hallucinogens have been known to precipitate the first anxiety attack in some patients.

a) True
b) False

30. Patients with panic disorder are often convinced that they have a cardiac or neurologic disorder and that their anxiety or nervousness is secondary to then-physical symptoms.

a) True
b) False

31. In the education and treatment of panic disorder, a physician should do all of the following except:

a) explain the biologic research on panic disorder
b) explain the effectiveness of medications
c) help patient understand that panic attacks can occur even when no apparent stress is present, because of the dysfunction of the autonomic nervous system
d) project an image of confidence in the diagnosis
e) discourage the patient from becoming dependent

32. Patients with panic disorder are one of the most difficult groups of patients to treat with medications. Useful treatment strategies to increase compliance include all of the following except:

a) advise the patient that he or she may have side effects from the medications
b) see the patient at least once a week and be available by telephone to answer questions about side effects
c) limit the medication dosage so as not to build resistance to the drug
d) give the patient books or articles to read about panic attacks

33. The goal of psychopharmacologic treatment is to

a) block spontaneous panic attacks
b) eliminate avoidance behavior and social phobias

34. Tricyclic antidepressants have been found very effective in the treatment of panic disorder. Within this group, which of the following medications has been found least effective?

a) trazodone
b) imipramine
c) desipramine
d) nortriptyline
e) amitriptyline

35. If the patient gets an excitatory or stimulant-like effect with imipramine or desipramine, which of the following would be the incorrect response?

a) increase the dosage to 150 mg of imipramine or desipramine
b) change to a less noradrenergic drug, such as 25 mg of nortriptyline
c) temporarily add a low dose ofalprazolam
d) switch to a monoamine oxidase inhibitor or benzodiazepine

36. Common side effects oftricyclic antidepressants include all of the following except:

a) dry mouth
b) constipation
c) memory dysfunction
d) increase in blood pressure
e) weight gain

37. Disadvantages of using benzodiazepines as a first-line antipanic drug include all of the following except:

a) Patients with panic disorder have a concurrent maj or depression and benzodiazepines are not effective antide¬pressants.
b) Some patients may abuse benzodiazepines.
c) serious side-effects
d) Benzodiazepines are more difficult to taper than are tricyclic antidepressants or MAOIs.

38. Several types of patients should not be treated with benzodiazepines. Select the correct response from the following:

a) patients with a history of polydrug or alcohol abuse
b) patients with personality disorders and chronic benign pain conditions
c) patients with concurrent major depression
d) all of the above
e) a and b

39. Main side effects of benzodiazepines include all of the following except:

a) sedation
b) orthostatic hypotension
c) psychomotor impairment
d) slurred speech and amnesia

40. Patients taking monoamine oxidase inhibitors should follow certain dietary restrictions to minimize the risk of side effects. One of the following foods, however, has not been proven to cause adverse interaction:

a) beer and wine
b) coffee, tea and other caffeine-containing beverages
c) cheese
d) beef or chicken liver
e) smoked or pickled fish, especially herring

41. Side effects of MAOIs include all of the following except:

a) sedation
b) hypertensive reactions
c) insomnia
d) orthostatic hypertension

42. Which of the following types of drugs is most difficult to taper in patients with panic disorder?

a) tricyclic antidepressant
b) MAOI
c) benzodiazepine

43. Even after successful drug therapy, studies have reported that anywhere from 30-90% of patients relapse within one year.

a) True
b) False

44. Should the patient relapse during withdrawal or soon after with drawal of one of the three classes of antipanic medications, which of the following actions should be taken?

a) Another six-to-twelve month course of medication is prescribed before a second attempt to taper medication is instituted.
b) augment medication with psychotherapy
c) increase the dosage of medication to just above the level at which relapse occurred
d) all of the above
e) a and c

45. Psychodynamic, marital or family therapy in patients with panic disorder should be used for all of the following reasons except:

a) decrease social and psychologic distress
b) improve self-esteem
c) reduce or eliminate maladaptive mechanisms such as avoidance, wishful thinking and passivity
d) take place of psychopharmacologic treatment

46. All of the following are examples of behavioral therapy for panic disorder except:

a) in vivo exposure to frightening situations
b) hyperventilation exposure and breathing training
c) group therapy and interaction with other patients of panic disorder
d) desensitization to the patient's own somatic symptoms

47. Which of the following classes of patients with panic disorder would not benefit from psychiatric consultation?

a) patients who tend to deny or minimize stressful life events and anxiety
b) patients who are unable to tolerate side effects of psychopharmacological medications
c) patients concurrently suffering from major depression with suicidal tendencies
d) patients who have serious medical illness, such as heart disease, diabetes, or chronic obstructive lung disease
e) patients with financial and marital problems