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Part III.

Abstract

Executive Summary

Overview

Chapter 1 - Guideline Development and Methodology

	Rationale for Guideline Developement-The Cost of Depression
	Methodological Background
	Specific Methodological Strategies
	Review of the Literature
	Meta-Analysis

Chapter 2 - Guideline: Aims of Treatment

	Benefits and Harms of Treatment
	Medications
	Psychotherapy
	Combination of Medication and Psychotherapy
	Electroconvulsive Therapy
	Clinical Management
	Improving Adherence to Treatment
	Measuring Outcome
	Declaring a Treatment Response or Failure
	Switching Versus Augmenting Treatments

Chapter 3 - Guideline: Strategic Planning for Acute Phase Treatment

	Objectives of Acute Phase Treatment
	Indiccations for Acute Phase Treatment
	Treatment Selection
	Selection of Medication
	Selection of Psychotherapy Alone
	Selection of Combined Treatment
	Select of ECT
	Treatment Refusal

Chapter 4 - Guideline: Acute Phase Management with Medication

	Indications for Acute Phase Medication
	Evidence of Efficacy
	Antidepressant Medication Selection
	Frequency of Visits
	Medication Dosage Adustments
	Antidepressant Drug Blood Levels
	Failure to Respond
	Continue Medication
	Switch Medication
	Augment Medication
	Add Psychotherapy
	Obtain a Consultation

Chapter 5 - Guideline: Acute Phase Management with Psychotherapy

	Obejectives and Indications
	Evidence for Efficacy
	Cognitive Therapy
	Behavioral Therapy
	Interpersonal Psychotherapy
	Martial Therapy
	Brief Dynamic Psychotherapy
	Factors Affecting Response to Psychotherapy
	Selection of a Psychotherapy
	Frequency of Visits
	Failure to Respond

Chapter 6 - Acute Phase Management with Medication and Psychotherapy

	Objectives and Indications
	Evidence of Efficacy
	Selection of a Combined Treatment
	Frequency of Visits
	Dosage Adjustments
	Failure to Respond

Chapter 7 - Guideline: Acute Phase Management with ECT

Chapter 8 - Guideline: Special Situations

	The Suicidal Patient
	Geriatric Depression
	Seasonal Depression
	Depression and Other Nonpsychiatric Medical Disorders
	Depression and Other Psychiatric Disorders

Chapter 9 - Guideline: Continuation and Maintenance Treatment Options

	Objectives and Indications for Continuation Treatment
	Objectives and Indications for Maintenance Treatment
	Continuation/Maintenance Phase Management with Medication
	Evidence of Efficacy
	Frequency of Visits
	Medication Dosage Adjustments and Antidepressant
	Symptom Breakthrough
	Discontinuation of Medication
	Continuation/Maintenance Phase Management with Psychotherapy
	Cognitive Therapy
	Behavioral Therapy
	Interpersonal Psychotherapy
	Marital Therapy
	Brief Dynamic Psychotherapy
	Factors Affecting Decisions about Continuation/Maintenance
	Frequency of Visits
	Symptom Breakthrough
	Continuation/Maintenance Phase Management with the Combination of Medication and Psychotherapy
	Evidence of Efficacy
	Discontinuation of Treatment
	A Second Opinion or Referral
	Primary Care Practitioners
	Patients and Families
	Consultations with Mental Health Care Professionals

References

Acronyms

Glossary

Contributors

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